Description
LigandAI, developed by Ligandal, is an advanced platform designed for the computational discovery and design of peptide binders. It leverages AI-driven technologies to generate de novo peptide sequences that can target specific proteins or cell types. The platform's core components include LigandForge, which uses single-pass discrete diffusion to generate up to 1,190 peptide binders per second, and DeltaForge, which provides thermodynamic scoring to predict binding affinities.
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Boltz-2, another integral part of LigandAI, performs structural validation using multi-GPU parallel processing. This ensures that the designed peptides are structurally viable for their intended targets. The platform is particularly adept at designing peptides for tissue-specific targeting, lipid nanoparticle (LNP) targeting, and mRNA delivery, making it a valuable tool for researchers in the fields of drug discovery and biotechnology.
LigandAI offers a range of pricing tiers to accommodate different user needs. The free tier provides 10,000 evaluation credits, allowing users to explore the platform's capabilities. For more extensive use, the Basic plan costs $799 per month, offering 75,000 credits and full access to LigandForge, DeltaForge, and Boltz-2. Academic institutions can opt for the Academia plan at $299 per month, while the Pro plan at $5,000 per month provides 500,000 credits and additional features such as BLI synthesis via Adaptyv Foundry.
The platform supports a wide array of targets, including over 20,000 human proteins, and integrates with databases like UniProt and AlphaFold DB. LigandAI's Predictive Interactomics® feature allows for the discovery of tissue-specific receptors using single-cell RNA-seq data, enhancing its utility in precision medicine. With 89 patent filings worldwide, LigandAI stands as a robust tool for peptide therapeutic design.
- CategoryScientific Discovery & Lab Tools
- Pricing ModelFreemium
- DeploymentCloud
- PlatformsWeb
LigandAI's Core Features
LigandForge peptide generation
DeltaForge thermodynamic scoring
Boltz-2 structural validation
Predictive Interactomics® target discovery
Tissue-specific targeting
LNP and mRNA delivery design
Multi-GPU parallel processing
Integration with UniProt and AlphaFold DB
How to use LigandAI?
Sign up: Create an account on LigandAI
Configure: Select target proteins or cell types
Use: Generate and validate peptide binders
Optimize: Refine designs based on validation results
LigandAI's Use Cases
- Peptide Therapeutics
- Protein Targeting
- LNP Design
- mRNA Delivery
- Receptor Discovery
