Description
AlphaFold Server is a web-service that generates highly accurate biomolecular structure predictions, including proteins, DNA, RNA, ligands, and ions. It is powered by the latest AlphaFold 3 model, which enhances the ability to model complex biomolecular interactions. Users can input various biological molecule types and receive detailed predictions about their structures and interactions.
The server allows for modeling structures that consist of multiple biological molecules, including proteins, DNA, RNA, and various ligands and ions. It supports a wide range of biologically common ligands and ions, as well as post-translational modifications of amino acids and nucleic acids. The modeling process is limited by a token system, where the total size of the job is capped at 5,000 tokens, ensuring efficient processing and accurate predictions.
AlphaFold Server is designed for non-commercial use and requires users to adhere to specific terms of service. Users can run up to 30 jobs per day, with the option to save jobs and submit them later if they exceed their quota. The server also provides confidence metrics for the predictions, allowing users to assess the reliability of the generated structures. These metrics include pLDDT, PAE, pTM, and ipTM scores, which help users interpret the accuracy of the predicted structures.
For those interested in customizing their predictions, AlphaFold Server offers options to use custom templates and multiple sequence alignments (MSAs). Users can upload their own templates and MSAs to enhance the prediction process, making it a versatile tool for researchers in the field of biomolecular modeling.
AlphaFold Server's Core Features
Accurate structure predictions
Supports proteins, DNA, RNA, ligands, ions
Custom templates and MSAs available
Confidence metrics provided
Non-commercial use only
30 jobs per day limit
Token limit of 5000
Web-based interface
How to use AlphaFold Server?
Input biological molecule types: Enter the desired proteins, DNA, RNA, or ligands.
Customize templates: Upload custom templates if needed for specific predictions.
Set up MSAs: Provide custom multiple sequence alignments to enhance prediction accuracy.
Submit job: Run the prediction job and wait for results to be processed.
AlphaFold Server's Use Cases
- Protein Interaction Modeling
- DNA Structure Prediction
- RNA Interaction Analysis
- Ligand Binding Studies
- Chemical Modification Modeling
